Amenorrhea: Causes, Symptoms, Diagnosis, and Treatment
Amenorrhea is the absence of menstrual periods in women of reproductive age. While it can sometimes be normal such as during pregnancy, breastfeeding, or menopause.
Amenorrhea may also be a sign of an underlying medical condition that requires evaluation and treatment.
Types of Amenorrhea
Amenorrhea is generally classified into two categories:
Primary Amenorrhea:
When menstruation has not started by the age of 15, even though other signs of puberty (such as breast development or pubic hair growth) have appeared.
Secondary Amenorrhea:
When a woman who previously had regular menstrual cycles stops having periods for three or more consecutive months, or for six months in women with irregular cycles.
Common Causes
The causes of amenorrhea vary depending on age, medical history, and lifestyle. They can be divided into natural, lifestyle-related, and medical factors.
Natural Causes
Pregnancy
Breastfeeding
Menopause
Lifestyle Factors
Significant weight loss or eating disorders
Excessive physical exercise (common in athletes)
High stress levels
Poor nutrition
Medical Causes
Polycystic Ovary Syndrome (PCOS): A hormonal imbalance that affects ovulation.
Thyroid Disorders: Both hyperthyroidism and hypothyroidism can interfere with menstruation.
Pituitary Gland Disorders: Tumors or dysfunction affecting hormone production.
Premature Ovarian Failure (Early Menopause): Ovarian function ceases before the age of 40.
Uterine Scarring (Asherman’s Syndrome): Scar tissue inside the uterus, often after surgery or infection.
Chronic Illnesses: Such as diabetes or celiac disease.
Symptoms
In addition to missed periods, women with amenorrhea may experience:
Headaches or vision changes
Hair loss or excessive hair growth
Acne or oily skin
Hot flashes or night sweats
Vaginal dryness
Changes in weight or appetite
Milky discharge from the breasts (galactorrhea)
When to See a Doctor
Consult a healthcare provider if you:
Have missed three or more consecutive periods and are not pregnant.
Have not started menstruating by age 15.
Experience additional symptoms such as fatigue, headaches, or vision problems.
Early evaluation is important to identify the cause and prevent complications such as infertility, osteoporosis, or hormonal imbalances.
Diagnosis
A doctor will perform a detailed medical history, physical examination, and may order tests such as:
Pregnancy test
Blood tests to measure hormone levels (FSH, LH, estrogen, prolactin, thyroid hormones)
Pelvic ultrasound to check for ovarian or uterine abnormalities
MRI or CT scan of the pituitary gland if a tumor is suspected
Treatment
Treatment depends on the underlying cause:
Lifestyle modifications: Improved nutrition, healthy weight management, and reduced stress or excessive exercise.
Hormonal therapy: To correct imbalances, including birth control pills or hormone replacement therapy.
Thyroid treatment: Medications to correct thyroid function.
Surgery: In cases of uterine scarring or pituitary tumors.
Fertility treatment: For women wishing to conceive.
Possible Complications
If left untreated, amenorrhea can lead to:
Infertility
Osteoporosis (bone loss) due to low estrogen levels
Cardiovascular issues related to hormonal imbalance
Emotional or psychological stress
Prevention & Management
Maintain a balanced diet and a healthy body weight.
Avoid excessive exercise without proper nutrition.
Manage stress through mindfulness, relaxation, or therapy.
Schedule regular gynecological check-ups.
Seek medical advice promptly for irregular menstrual cycles.
Amenorrhea is not a disease, but a symptom that can point to various underlying conditions. Identifying the cause early allows for effective treatment and helps maintain overall reproductive and hormonal health.
If you experience prolonged absence of periods, consult a qualified gynecologist or endocrinologist for proper evaluation and management.

